The abundance of a chemical (if chemical synthesis is not known).
A biochemical event resulting in a new chemical product.
The movement of a molecule out of a cell (by more specific means than secretion).
The bending and positioning of a molecule to achieve conformational integrity.
The splitting of a molecule via the specific use of water.
The movement of a molecule into a cell (by more specific means than uptake).
The genetic alteration of a gene product.
Any general biochemical or molecular event.
Overall propensity of molecules to degradation.
The movement of a molecule into a cell (by less specific means than import).
Involving the use of two or more chemicals simultaneously.
The processing or splitting of a molecule, not necessarily leading to the destruction of the molecule.
The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule.
For ligands that bind to signal transducing receptors, consider the molecular function term 'receptor binding ; GO:0005102' and its children.
A protein glycosylation process in which a sugar unit is added to a protein via the N4 atom of peptidyl-asparagine, the omega-N of arginine, or the N1' atom peptidyl-tryptophan.
protein amino acid N-linked glycosylation
A protein glycosylation process in which a sugar unit is added to a protein via the hydroxyl group of peptidyl-serine, peptidyl-threonine, peptidyl-hydroxylysine, or peptidyl-hydroxyproline, or via the phenol group of peptidyl-tyrosine, forming an O-glycan.
protein amino acid O-linked glycosylation
The covalent attachment of lipid groups to an amino acid in a protein.
For non-covalent interactions with a lipid, consider instead the term 'lipid binding ; GO:0008289' and its children.
The directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore.
The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.
Note that metabolic processes do not include single functions or processes such as protein-protein interactions, protein-nucleic acids, nor receptor-ligand interactions.
The process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA.
The chemical reactions and pathways resulting in the breakdown of substances, including the breakdown of carbon compounds with the liberation of energy for use by the cell or organism.
The process in which a gene's sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Some protein processing events may be included when they are required to form an active form of a product from an inactive precursor form.
The protein modification process in which a glutathione molecule is added to a protein amino acid through a disulfide linkage.
The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide.
The process in which one or more ubiquitin groups are added to a protein.
The process in which a SUMO protein (small ubiquitin-related modifier) is conjugated to a target protein via an isopeptide bond between the carboxyl terminus of SUMO with an epsilon-amino group of a lysine residue of the target protein.
small ubiquitin-related protein 1 conjugation
The covalent addition of a nitric oxide group to an amino acid within a protein.
The addition of a nucleotide to a protein amino acid.
The covalent attachment of a prenyl group to a protein; geranyl, farnesyl, or geranylgeranyl groups may be added.
The covalent attachment of a farnesyl group to a protein.
The covalent attachment of a palmitoyl group to a protein.
The covalent attachment of a myristoyl group to a protein.
The modification of a protein by amino acid glucuronidation.
The process in which a methyl group is covalently attached to a molecule.
A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus.
The controlled release of a substance by a cell, a group of cells, or a tissue.
The addition of a carbamoyl group to a protein amino acid. A carbamoyl group is the acyl group -CO-NH2.
Any process in which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in a specific location.
establishment and maintenance of localization
establishment and maintenance of position
establishment and maintenance of cellular component location
establishment and maintenance of substance location
establishment and maintenance of substrate location
The addition of a sulfate group to a molecule.
The covalent attachment of a glycosyl residue to a substrate molecule.